No matter how much skincare you apply, does your skin still look tired? Are enlarged pores difficult to improve, while acne scars remain deeply indented? This may be because the skin’s underlying structure has been damaged. Dermatology now offers innovative injectable skin boosters (Skin Booster) designed to repair the skin as deeply as the DNA level. One example is the Vitaran program, which has gained attention for restoring damaged skin so that it looks plump, dewy, and healthy, without the intense stinging associated with earlier treatments. Today, The Vanish Clinic introduces this procedure in detail.
Key Takeaways
- Vitaran is a skin-rejuvenation innovation containing a concentrated 2% solution of purified Polynucleotide (PN) extracted from salmon and trout DNA. It works at the cellular level to repair the skin and stimulate sustainable skin-cell renewal.
- A key feature is its proprietary Pain Control Innovation, which helps balance pressure within the skin. This can reduce pain and stinging during injection by up to 80% compared with earlier PN products, making the procedure more comfortable.
- There are two main options: Vitaran I, which emphasizes precision in delicate areas such as around the eyes, and Vitaran II, which is designed for larger areas such as the entire face, neck, or backs of the hands. Both versions contain the same concentration of the active ingredient.
- It addresses a broad range of skin concerns, including reducing redness, soothing inflamed skin, softening the appearance of acne scars, tightening the appearance of pores, and improving elasticity. Combining the procedure with laser programs such as PICO Laser or Discovery PICO at The Vanish Clinic may help produce faster and more noticeable results.
What is the Vitaran program?
VITARAN is an injectable skin-booster innovation made with purified Polynucleotide (PN). It was developed and manufactured in South Korea under international medical standards by BR Pharm. The extract is derived from arranged DNA fragments from fish in the Salmonidae family—salmon and trout—raised in a clean and safe closed system.
In simple terms, it acts as a “Biostimulator,” creating a supportive scaffold for skin cells. Vitaran has become widely discussed in dermatology because it can address redness and acne scars while effectively rejuvenating the skin. Its major advantage over older PN products is its ability to noticeably reduce pain and stinging during injection.
What does the Vitaran program contain?
Its main ingredient is 2% Polynucleotide Sodium (20 mg/mL), a proportion that research has identified as optimal for stimulating the skin. The product undergoes extensive purification, reducing contaminating proteins to below 0.2% to lower the likelihood of allergic reactions or inflammation. This allows the body to use it immediately. It is considered safe and has received European CE Mark certification.
What is Polynucleotide (PN)?
Polynucleotide (PN) is a molecular chain of nucleotides linked together to form a long structure. It is extracted from fish species whose molecular DNA structure is stated to be up to 95% similar to that of humans. Cutting and extracting this material to achieve high purity is highly difficult and complex in a biological laboratory.
From an academic and medical perspective, research indicates that when PN is injected into the dermis, its molecules bind to receptors known as Adenosine A2A Receptors. This binding stimulates the formation of new capillaries (Angiogenesis), helping previously thin and weakened skin become denser. Oxygen and nutrients can then be delivered to skin cells more effectively, supporting repair of the skin’s structure from within.
What are the benefits of Vitaran, and how many versions are available?
Vitaran’s key qualities are its combined ability to support tissue repair, reduce inflammation, and combat free radicals. To target concerns in different areas precisely, the product is currently available in two main versions.
Vitaran I Program
Vitaran I comes in a box containing two 1 mL syringes, for a total of 2 mL. This version is designed for areas requiring particular delicacy and highly precise distribution. It is suitable for small, very delicate areas such as the skin around and beneath the eyes, shallow nasolabial folds, or Fine Lines on the face. The gel spreads smoothly through thin layers of skin without forming raised lumps. It helps reduce dark circles and improve skin density so the under-eye area appears fuller.
Vitaran II Program
Vitaran II comes in a box containing two 2 mL syringes, for a total of 4 mL. It is designed to treat and rejuvenate Larger Treatment Areas such as the entire face, neck, décolletage, or backs of the hands. It is suitable for people with widespread skin deterioration, loss of elasticity, sagging, or acne scars across the face. This version’s gel helps firm the tissue structure, smooth the skin, and restore density and plumpness across larger areas.
The Vanish Clinic’s summary: Vitaran I and Vitaran II have exactly the same ingredients, quality, and 2% PN concentration. The only differences are syringe size and the total volume in each box. Vitaran I excels in precision for small areas with thin skin, such as around the eyes, while Vitaran II provides efficient product distribution when rejuvenating larger areas such as the entire face and neck.
What concerns can the Vitaran program address?
Vitaran’s mechanism can produce noticeable changes in several aspects of the skin, including the following:
1. Repairs the skin structure and softens acne scars
Vitaran accelerates the release of cell-repair substances and increases density within the dermis. This helps reorganize collagen fibers beneath the skin, gradually filling indented tissue and acne scars from within. Rough, uneven facial skin therefore becomes naturally smoother and more refined.
Because of its Anti-inflammatory properties, the PN in Vitaran inhibits the release of substances that trigger irritation within the skin. It helps soothe skin prone to redness, reduce post-acne redness, and accelerate recovery from chronic inflammation.
3. Improves elasticity and softens fine lines
Stimulating fibroblast activity increases elastin production. Elastin is an important protein for Skin Elasticity, helping fine lines caused by aging or loss of firmness gradually fade while the skin appears tighter and denser.
4. Refines the appearance of pores and balances moisture
Vitaran helps balance the function of sebaceous glands beneath the skin, controlling excessive oil production while improving the cells’ ability to retain water. The skin consequently appears smoother and more refined, pores look tighter, and the complexion gains a healthy, dewy glow.
Who is the Vitaran program suitable for?
Vitaran skin rejuvenation is designed for people experiencing skin deterioration and is comparable to an intensive nourishing treatment. It is suitable for:
- People with acne scars, uneven skin, or rough marks caused by squeezing or extracting acne who want a smoother, more refined complexion.
- People with red or dark acne marks, inflamed skin, or skin prone to irritation.
- People with thin, weakened skin caused by frequent laser treatments who want to strengthen the skin barrier.
- People with dry, rough, dehydrated skin that does not readily absorb skincare or hold makeup well.
- People beginning to develop age-related lines, including fine lines around the eyes, forehead, or corners of the mouth.
- People who want their overall complexion to look brighter and plumper without altering their natural facial shape.
How does the Vitaran program differ from other Skin Boosters?
Although today’s Skin Boosters generally share the goal of creating a hydrated, radiant complexion, Vitaran differs clearly from other brands when its ingredients, technology, and specific mechanism are examined more closely.
How does the Vitaran program differ from Rejuran?
- Vitaran is less painful than Rejuran: Rejuran is known for being painful during injection, whereas Vitaran incorporates Pain Control Innovation to reduce changes in Micro-Osmotic pressure after injection. This reduces burning and pain by up to 80%, making the experience more comfortable for patients.
- Vitaran has a lower likelihood of allergy than Rejuran: Both use PN at a concentration of 2%, but Vitaran uses extracts from salmon and trout raised in a closed system with strictly controlled purity standards. This results in very low levels of foreign proteins and a lower likelihood of allergic reactions.
- Different results: Rejuran is known primarily for creating an overall Glass Skin glow, while Vitaran focuses more heavily on reducing redness, soothing inflamed skin, and accelerating the repair of acne-scar tissue.
How does the Vitaran program differ from Plinest?
- Polynucleotide (PN) origin: Plinest is a European PN product from Italy, while Vitaran is a South Korean innovation with a formulation developed to better address Asian skin.
- Greater suitability for injection into thin skin: Plinest generally focuses on increasing skin tension and vertical density, giving it a certain degree of viscosity. The molecules in Vitaran I, by contrast, have been adjusted to make the product more fluid and allow it to spread more gently through superficial skin layers. When injected into very thin areas such as around the eyes, it blends smoothly with the skin immediately, without the risk of thick raised bumps, and causes less pain because of its Pain Control system.
How does the Vitaran program differ from Pluryal Densify?
- Product ingredients: Pluryal Densify is a Hybrid Skin Booster combining Polynucleotide (PN), Hyaluronic Acid (HA), and Mannitol in a single syringe. Vitaran I contains Pure PN (100% purified polynucleotide) with no added HA.
- Treatment areas: Pluryal Densify focuses on adding volume and immediately hydrating and plumping the skin through the properties of HA, but it is not recommended for injection around the eyes. Vitaran I, in contrast, focuses directly on repairing deteriorated cells and can be safely injected into the skin around the eyes to address dark circles and under-eye wrinkles.
Are Vitaran injections painful?
To answer honestly, any procedure involving needles can cause some sensation, particularly in areas where the skin is thin. With the Vitaran program, however, the pain is considered minimal and tolerable. The product’s technology balances pressure beneath the skin, preventing the burning sensation that occurred when older PN products were injected.
How much does the Vitaran program cost?
For the Vitaran program, The Vanish Clinic currently offers an introductory promotion at only 4,999.- per 1CC.
How many CC of Vitaran are injected per session?
The appropriate amount depends on the skin’s condition and the area being rejuvenated. For a specific area, such as around the eyes or shallow nasolabial folds, 1-2 CC is generally used, and the physician will select Vitaran I. For rejuvenation across the entire face and neck, the physician will recommend 2-4 CC per session and select Vitaran II to provide comprehensive distribution. A course of 3-4 sessions at intervals of 2-4 weeks is recommended for noticeable results.
Steps in the Vitaran program
- Meet with a specialist physician for a skin assessment, planning of the areas requiring particular attention, and determination of the appropriate number of CC.
- Cleanse the face to remove impurities and makeup and prepare the skin.
- Apply topical anesthetic for approximately 45-60 minutes to keep the patient as comfortable and relaxed as possible during the procedure.
- The physician carefully injects Vitaran into the dermis using a targeted technique.
- Cleanse the skin again, apply a cold compress to soothe it, and apply a nourishing cream to reduce post-treatment redness.
How to prepare for the Vitaran program
- Avoid pain relievers, aspirin, ibuprofen, vitamin E, fish oil, and supplements that promote blood circulation for approximately 3-5 days before the procedure to reduce needle marks and bruising.
- Avoid alcoholic beverages and saunas for 24 hours before the appointment.
- Always tell the physician before the procedure if you have an underlying medical condition, a history of drug allergies, or a severe allergy to seafood or fish, as the product contains fish-derived material.
How to care for yourself after the Vitaran program
- Avoid washing your face with very hot water and avoid heavy makeup during the first 24 hours after treatment to allow the injection sites to close completely.
- Avoid touching, wiping, rubbing, or scratching the face forcefully. Pat the skin dry gently.
- Avoid intense sunlight, strenuous exercise that causes heavy sweating, and saunas during the first 48 hours.
- Apply moisturizing skincare products and use SPF 50+ sunscreen every day.
- Drink approximately 2-3 liters of clean water per day to help the cellular repair process work at full efficiency.
Why have the Vitaran procedure at The Vanish Clinic?
Choosing where to receive skin care is extremely important. At The Vanish Clinic, we focus on providing services according to the highest medical safety standards. Every box of Vitaran used is 100% authentic and verifiable, legally imported, and administered by specialist physicians with an in-depth understanding of the skin’s structure. This allows injection points to be planned and the product distributed evenly in the areas of concern, whether the focus is rejuvenating dark under-eye areas or filling indented acne scars.
The Vanish Clinic can also recommend integrated treatment combinations, such as Vitaran injections alongside Pico laser treatments. The PN helps accelerate post-laser skin healing, reduce redness, and promote stronger, smoother, more youthful-looking new tissue more quickly.
A short video explaining the Vitaran program by Dr. Pantha Ritjana, medical license no. ว.72875.
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Reviews of the Vitaran program procedure at The Vanish Clinic from real clients
Frequently Asked Questions About Vitaran (FAQ)
– How many days after a Vitaran injection will results appear?
Patients may begin to notice smoother, softer, and more hydrated skin within 3-7 days after injection. More noticeable changes in skin-structure repair, the softening of acne scars, and the appearance of tighter pores should become fully apparent within 2-3 weeks.
– How long do the results of Vitaran injections last?
After completing the procedure as recommended by the physician, the rejuvenating effects and overall improvements in the skin may last approximately 6-9 months, depending on the individual’s original skin condition and aftercare.
– Can you resume normal activities after a Vitaran injection?
You can resume normal daily activities immediately after the procedure. Small raised areas caused by the product or redness from the needle may appear after injection. These are considered normal and should gradually subside on their own within 1-2 days, with no lengthy recovery period required.
– Is Vitaran dangerous?
Vitaran is not considered dangerous because it is a naturally derived, purified Polynucleotide extract stated to have up to 95% compatibility with human DNA. It has received certification from both the Thai FDA and the European CE Mark. The product biodegrades naturally without leaving residue or forming permanent lumps.
– Who should take precautions before receiving Vitaran?
Those who should exercise particular caution and consult a physician thoroughly before the procedure include people with a history of severe fish or seafood allergies, women who are pregnant or breastfeeding, people with an infected wound in the planned injection area, and people with an underlying condition involving immune deficiency.
